Rie Matsushima-Nishiwaki Selected Research

Retinoid X Receptor alpha

10/2007	Expression of retinoid X receptor alpha is decreased in 3'-methyl-4-dimethylaminoazobenzene-induced hepatocellular carcinoma in rats.
8/2003	Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid.
2/2002	Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma.
1/2002	Retinoids in liver fibrosis and cancer.

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Rie Matsushima-Nishiwaki Research Topics

Disease

28	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2002
18	Neoplasms (Cancer) 01/2020 - 01/2002
5	Glioma (Gliomas) 10/2014 - 07/2008
5	Carcinogenesis 02/2013 - 01/2005
4	Bone Resorption 01/2021 - 04/2007
4	Colonic Neoplasms (Colon Cancer) 02/2013 - 11/2007
3	Osteoporosis 12/2020 - 01/2008
3	Stroke (Strokes) 03/2020 - 11/2009
3	Inflammation (Inflammations) 06/2015 - 01/2005
3	Thrombosis (Thrombus) 07/2010 - 01/2008
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 05/2016
2	Chronic Pain 12/2020 - 08/2020
2	Low Back Pain (Lumbago) 12/2020 - 08/2020
2	Diabetes Mellitus 01/2015 - 08/2009
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2014 - 11/2009
1	Cerebral Hemorrhage 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Postmenopausal Osteoporosis 01/2022
1	Thrombocytopenia (Thrombopenia) 01/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 10/2021
1	Musculoskeletal Pain 10/2021
1	Fibromyalgia (Fibrositis) 10/2021
1	Bone Fractures (Bone Fracture) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2020
1	Necrosis 04/2017
1	Hypoxia (Hypoxemia) 02/2016
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2016
1	Atrial Fibrillation 01/2016

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2004
12	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2017 - 06/2007
8	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 01/2005
7	3,7,11,15- tetramethyl- 2,4,6,10,14- hexadecapentaenoic acidIBA 03/2007 - 01/2002
6	RetinoidsIBA 10/2007 - 01/2002
5	Phosphotransferases (Kinase)IBA 01/2021 - 09/2009
5	p38 Mitogen-Activated Protein KinasesIBA 06/2012 - 08/2009
5	HSP27 Heat-Shock ProteinsIBA 12/2011 - 11/2005
4	JNK Mitogen-Activated Protein KinasesIBA 01/2021 - 03/2010
4	MitogensIBA 01/2021 - 03/2010
4	Interleukin-6 (Interleukin 6)IBA 04/2017 - 11/2009
4	CytokinesIBA 01/2015 - 01/2002
4	CollagenIBA 01/2015 - 01/2002
4	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2007 - 01/2002
4	Retinoid X Receptors (Retinoid X Receptor)IBA 12/2007 - 02/2002
4	LigandsIBA 11/2007 - 02/2002
4	Retinoid X Receptor alphaIBA 10/2007 - 01/2002
4	Vitamin A (Retinol)FDA LinkGeneric 01/2005 - 01/2002
3	Protein Kinase CIBA 01/2021 - 07/2008
3	Antineoplastic Agents (Antineoplastics)IBA 12/2011 - 05/2004
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2010 - 07/2008
3	ErbB Receptors (EGF Receptor)IBA 09/2009 - 10/2008
3	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 09/2009 - 10/2008
3	TeaIBA 09/2009 - 04/2007
2	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2022 - 01/2021
2	Serotonin (5 Hydroxytryptamine)IBA 10/2021 - 12/2020
2	Duloxetine Hydrochloride (Cymbalta)FDA Link 10/2021 - 12/2020
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 10/2021 - 12/2020
2	Small Heat-Shock ProteinsIBA 01/2021 - 01/2016
2	OsteoprotegerinIBA 01/2021 - 01/2017
2	rho-Associated KinasesIBA 01/2021 - 11/2009
2	Olive OilIBA 03/2020 - 07/2019
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2020 - 01/2018
2	PolyphenolsIBA 07/2019 - 08/2009
2	LipidsIBA 01/2018 - 10/2008
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2017 - 01/2013
2	Protein Kinases (Protein Kinase)IBA 10/2014 - 03/2010
2	InterleukinsIBA 10/2014 - 03/2010
2	Mitogen-Activated Protein KinasesIBA 01/2013 - 11/2011
2	Serine (L-Serine)FDA Link 09/2009 - 07/2008
2	Catechin (Z 7300)IBA 08/2009 - 04/2007
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 07/2008 - 03/2007
2	InterferonsIBA 01/2005 - 05/2004
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 04/2004 - 01/2002
2	LectinsIBA 04/2004 - 01/2002
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	Thrombopoietin (c-mpl Ligand)IBA 01/2022
1	Estrogens (Estrogen)FDA Link 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	IncretinsIBA 01/2022
1	Hormones (Hormone)IBA 01/2022
1	Selective Estrogen Receptor Modulators (SERM)IBA 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	Estrogen ReceptorsIBA 01/2022
1	AntipyreticsIBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2021
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 12/2020
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 09/2020
1	Tramadol (K315)FDA LinkGeneric 08/2020
1	QuercetinIBA 01/2020
1	3-hydroxyflavoneIBA 01/2020
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2018
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2018
1	Thrombin Receptors (Thrombin Receptor)IBA 05/2016
1	MimosineIBA 02/2016
1	Amino Acids FDA Link 02/2016
1	Factor Xa (Coagulation Factor Xa)IBA 01/2016
1	ResveratrolIBA 06/2015
1	AntioxidantsIBA 06/2015

Therapy/Procedure

4	Chemoprevention 11/2007 - 01/2002
3	Drug Therapy (Chemotherapy) 12/2011 - 01/2002